Novak is in 10 straight grandslam semi-final, and he is second only to the all-time record holder ROGER FEDERER who has made 23 straight semi-final appearances. I don't think Novak will beat that record. Its impossible.
The only player that can trouble Novak in the US Open is Murray. I would love to see a Murray-Novak final. I am pretty sure Novak will beat Ferrer but Berdych vs Murray should be tough.