What is Sjögren's syndrome? Sjögren's syndrome (pronounced SHOW-grins) is one of the most prevalent autoimmune diseases. It’s a chronic condition in which the person’s white blood cells attack the body’s moisture-producing glands. The syndrome often strikes in tandem with other autoimmune conditions, including rheumatoid arthritis and lupus (a disease marked by chronic inflammation of organs and a butterfly rash across the nose).
What are the symptoms? The two classic hallmarks of Sjögren's syndrome are dry eyes that feel itchy or gritty, as if there’s sand in them, and a dry cottony mouth that makes it hard to swallow. Other symptoms include joint pain, swelling or stiffness, swollen salivary glands (particularly the ones behind the jaw and in front of the ears), dry nose or nosebleeds, heartburn, brain fog (trouble concentrating or remembering), tooth decay, abnormal liver function, numbness or tingling in the hands and feet, extreme fatigue, skin rashes, vaginal dryness, persistent bronchitis, pneumonia or lung disease, reports the Sjögren's Syndrome Foundation.
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How serious is Sjögren's syndrome? The disease can be mild to severe, but usually isn’t fatal. Patients need to be monitored for potential complications, including organ involvement, related autoimmune disease, dental problems (which are more common in people with Sj&
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